Elevating Innovation and Empowering Disruptive Founders

We fund University of Colorado Startups to transform great ideas into global successes.


About Buff Gold Ventures


You Dream It

We back bold thinkers and problem solvers from CU Boulder, funding the early stages of the next generation of disruptive technologies.


We Support it

Through strategic investment and hands-on collaboration, we help transform high-potential startups into impactful, valuable businesses.


We Elevate It

The success of our portfolio companies delivers meaningful returns—fueling further innovation and rewarding our partners.


Buff Gold Ventures supports University of Colorado entrepreneurs to create transformative companies


Investment Strategy


You Dream It

We back CU Boulder founders—faculty, students, alumni and startups licensing CU intellectual property.


We Support it

We seek high-potential, disruptive technologies that address large-scale challenges and are led by bold, execution-focused founders who are committed to building at scale.


We Elevate it

We provide Pre-Seed, Seed, Series A capital, follow-on capital and assist with syndication—ensuring our portfolio companies achieve meaningful growth and deliver strong returns for our partners.


Ready to take your startup further?
Let’s talk strategy

Portfolio


POLARIS ELECTRO-OPTICS

Ferroelectric nematic liquid crystals and device reference designs for CMOs foundries for enhanced electro-optic modulators.

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LongPath Technologies

Installing laser/sensor networks to provide the low cost detection and quantification of specific emission sources across large areas

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SinusLogic™

Innovation for chronic rhinosinusitis patients

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VitriVax

Novel technology platform delivering thermostable multi-dose vaccines in a single shot

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Tynt Technologies

Dynamic tining windows utilizing proprietary Reverse Metal Electrodeposition technology to control solar glare and passive heat in windows

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Think Bioscience

Genetically programming microbial systems to build small molecule therapeutics for elusive drug targets


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Vitro3D

Revolutionizing Volumetric 3D printing
for multiple verticals

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In the News


Post Register • 2/25/2025

LongPath Technologies Secures Landmark EPA Approval for Continuous Monitoring of Methane


Smart Business Dealmakers • 10/24/2024

Sally Hatcher & Mark Lupa Honoredin Denver Dealmakers of the Year List



BUSINESS WIRE • 12/4/2024

VitriVax Awarded $3.6M Grant for Polio VaccineDevelopment



7/25/2024

LongPath Technologies Finalizes $162.4 Million DOE Loan to Expand Nationwide Methane Emissions Monitoring Network

CU Boulder • Full Article

9/9/2024

Polaris Announced as 2024 IC Taiwan Winner

IC Taiwan Challenge • Full Article


7/25/2024

Think Bioscience among six CU Boulder startups selected to present at Rocky Mountain Life Science Investor Conference

CU Boulder • Full Article


5/30/2024

Gov. Jared Polis signs quantum industry bill on campus

CU Boulder • Full Article →

4/26/2024

Hickenlooper pushes to keep Colorado's lead in quantum development

KOAA News 5 • Full Article →


4/19/2024

Venture Partners Annual Report highlights a growing innovation pipeline & national recognition

CU Boulder • Full Article


5/7/2024

Think Bioscience extends Seed Round to accelerate pocket-finding platform

PR News Wire • Full Article →


Browse our complete collection of featured news articles


Our Team

Mark Lupa

  • Mark Lupa, PhD holds a BS from Northwestern University, an M Phil from the University of Sussex, England in Biomedical Engineering and a PhD in Pharmacology from the University of Lund, Sweden. He conducted neuroscience research for fifteen years at institutions worldwide, including at UCSF and the University of Colorado, before bringing together the founding team of Tabernash Brewing, an early craft brewery in Colorado.

    He was a partner at Tango, a private investment firm, before becoming founder and Managing Director of High Country Venture, a venture capital firm in Boulder, Colorado. Mark has served as founding member of the Board of Directors of Taligen Therapeutics (ALXN), Mosaic Bioscience, Sinopsys Surgical, Trisalus Life Sciences (TLSI), VetDC (ELAN), Codebreaker and Vitro3d. Currently, Mark is Managing Partner at Buff Gold Ventures, an investment firm focusing on Deep Tech startup companies coming out of the University of Colorado.

Sally Hatcher

  • Sally Hatcher, J.D. is a venture capital investor, board member, serial entrepreneur, and startup accelerator faculty member. Her current work as Managing Partner of Buff Gold Ventures stems from extensive experience founding and managing her own startups, Precision Photonics Corp. and MBio Diagnostics, and senior management in two more hardware-enabled data companies.

    She has significant experience training deep tech founders to become the next generation of innovators solving critical problems including climate change, quantum technologies, and drug discovery. Her work with the DOE, NSF and NIH led to her position standing up the commercialization strategy for the University of Colorado for all innovation-enabled startups, including the I-Corps Hub, Research to Market, Mentor Accelerator (now Embark), Ascent Deep Tech Accelerator, and diverse programs on founding and funding startups. Sally also enjoys non-profit board work, volunteering for community events, sculling, and adventures across the West.

Tasso von Windheim

  • Tasso is a scientist and entrepreneur with a strong background in deep-tech commercialization. As a co-founder of Undercover Colors, a company dedicated to reducing the rates of drug-facilitated sexual assault, he’s experienced in bringing deep-tech out of the lab and into the market

    He has a PhD in electrical and computer engineering from Duke University, and a B.S. in material science engineering from NC State University. After work, you can find Tasso hiking around the foothills with his dog Gryphon, or fishing the Boulder Creek.